Journal Summary

Journal: Clinical and Experimental Dermatology

Welcome to the first journal summary for Skin Care Cymru.

The aim of this is to provide a brief overview of the latest developments in the medical journals of the British Association of Dermatologists and occasionally some from other publications that are of interest. To note, there is already a freely available plain language summary of the British Journal of Dermatology available at the website This is not meant to be a replacement for this, rather to augment it. This is also not a comprehensive summary but some of the more interesting articles I wanted to share.


This is a personal interpretation of the journal as I see it. Whilst in all likelihood, the information is correct, there may be errors in interpretation which hopefully will be kept to a minimum.

 Pemphigus and associated diseases

Authors: K. Heelan, A.L. Mahar, S. Walsh, N.H. Shear

Pemphigus is a rare skin disease that causes thin blisters to appear on the skin and is very itchy. It is similar to the relatively more common pemphigoid but differs in that the blisters are less tense and is more resistant to treatment. This studylooked at 295 patient records and found people with pemphigus were more likely to have high blood pressure, diabetes, thyroid problems, cancer, asthma and rheumatoid arthritis. Other diseases also coexisted but were less common.

Psoriasis associated with cardiovascular disease and metabolic syndrome

Authors: J. Skivern, P. Philipsen, G. Therming

It has long been established that people with psoriasis are more likely to have heart disease and are at higher risk of stroke. They are more likely to have what is known as “metabolic syndrome” whereby someone is at higher risk of diabetes and high blood pressure. This study demonstrated that patients did not necessarily know the risk to their health with respect to this and were not aware of necessary changes in lifestyle such as exercise and weight loss.

 A new treatment for Scabies

Authors: S.E. Park, Y. Her, S.S. Kim, C.W.Kim

Scabies is a very itchy skin caused by a mite that burrows under the skin. It is spread by skin to skin contact. These investigators evaluated the effectiveness of a solution of 1% lindane (which is often used to treat woodworm) and found it to be an effective treatment for scabies.

 Genetic causes for acne

Authors: L. Li, Y. Wu, L. Li, Y.F. Cai, L. Geng, X.H. Gao, H.D. Chen

Acne is a disorder of the skin that has a multifaceted cause including over production of cells at the openings of hair follicles. This study found that an inherited genetic change could contribute to getting acne. It has been suggested that acne does run in families more but this study has found a possible gene that could contribute to this.

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